Synthesis, characterization and antibacterial activity of new Hg(II) complex containing ∝-keto stabilized phosphonium yllide

Phosphorus ylides are important reagents in organic chemistry, especially in the synthesis of naturally occurring products with biological and pharmacological activities.Due to the high versatility from the applications as pharmaceutical and biological active agents point of view and also wide scope of suitability in industrial and chemical processes, The synthesis and usability of the metalated phosphorus ylides have attracted the synthetic chemist‘s attention[1,2].Herein, a new stable phosphorus ylide with formula of (ptolyl) 3P=CHCOC6H4(p-CN) was synthesized (Fig.1) and a series of binuclur complexes based on metalated phosphorus ylides were prepared through the reaction of (p-tolyl)3 P=CHCOC6H4(p-CN)with mercury(II) halides in equimolar ratios using MeOH as solvent (Fig.2). The structure of the prepared phosphorus ylide and complexes were confirmed by using IR, 1H, 31P and 13C NMR analys. In another study, the antibacterial applicability of the synthesized mercury (II) complexes was successfully explored against both the five Grampositive and four Gram-negative bacteria.