پديدآورندگان :
Sadat Alahmadi Maryam maryamsa_sam@yahoo.com Shahid Bahonar Branch, Farhangian University, Hamedan, Ira , Alahmadi Seyyedeh Fatemeh - Tabriz University, Tabriz, Iran , Rahimi Alireza - Islamic Azad University, Arak, Iran , Paktinat Saba - Shahid Bahonar Branch, Farhangian University, Hamedan, Iran
چكيده فارسي :
A new technique, namely dynamic headspace liquid-phase microextraction, has been developed for the extraction of 1,4-dioxane in cosmetic and hygiene samples followed by gas chromatography–flame ionization detection. [1] In this method, the sample is mixed with acetone as a diluent solvent. Then, a few microliters of n-octanol are added into a home-made extraction vessel placed in the headspace of the sample. [2] By heating, the target analyte is transferred to the headspace of the sample and then extracted into n-octanol. Under the optimized conditions, the method showed a good linearity in the range of 3.24–1000 μg kg−1 with a coefficient of determination 0.998. Figures of merit such as enrichment factor of 375, extraction recovery of 94 %, limits of detection and quantification 0.97 and 3.24 μg kg−1, respectively, and relative standard deviation 4.7 % (n = 6, C = 30 μg kg−1) of the proposed method were satisfactory for determination of the target analyte. Finally, the method was successfully applied in determination of 1,4-dioxane in various cosmetic and hygiene samples including shampoo, toothpaste, lotion, washing liquid, and dishwashing liquid. [4,3]
