Venoms and their application in drug design

When most people think about snake or other venomous animals, often deadly reactions come to their mind. This however, is not always the case. Venom can be used beneficially in a variety of situations. It is interested in exposing the positive side of venom, and learning more about its numerous uses.Over the last 100 million years, venomous animals learned to adapt these proteins and convert them into toxins. Venom contains hundreds of chemical and potent toxins which show different pharmacological effects because they have specific interaction with a macromolecular target in the body also they provide important tools in studying receptors, ion channels, and enzymes. Venoms have been used medicinally since the 1st Century AD. Native American uses Rattlesnakes for treatment or management of several medicinal situations. Chines, used snake skin and oil to treat a variety of illnesses, including hemorrhoids, sore throats, and eye infections. Because of developing a facility for the rapid screening of chemicals on cell-based and molecular assays, discovery of new toxins have stimulated many drug discovery projects, with some notable successes. Such as captopril an anti-blood pressure from the venom of Brazilian viper, Prialt an analgesics for chronic pain from the venom of cone snail, Controstatin an anti-cancer drug from the venom of copper head snake, Chlorotoxin from death stalker scorpion venom which sticks strongly to tumour cells and fight cancer cells etc. This topic is of a great medical importance because it has the possibility of producing cures to a large number of diseases. In conclusion, research on venoms could open a window to revolutionize medicine. Venoms have several medical benefits, and many more discoveries about its uses are sure to be made in the near future.