شماره ركورد كنفرانس :
4014
عنوان مقاله :
Enhanced electrochemical signal of BUP drug on a magnetic nano-mound structured surface
پديدآورندگان :
Farmany Abbas a.farmany@ut.ac.ir University of Tehran , Mahdavi Hossein a.farmany@ut.ac.ir University of Tehran
كليدواژه :
Buprenorphine , CS , MNCs , CP electrode , Voltammetry
عنوان كنفرانس :
دوازدهمين سمينار سالانه الكتروشيمي ايران
چكيده فارسي :
Herein, we report a highly sensitive voltammetric determination of buprenorphine using a citrate
stabilized magnetic nanocrystal (CS-MNCs) modified carbon paste electrode (CP). The
buprenorphine electro-oxidation peak current ip at CS-MNs/CP electrode was 10 fold higher than
that of unmodified CP electrode. CS-MNCs/CP electrode detects buprenorphine in the linear range
of 0.02-68.0 μM with a detection limit (DL) of 4.3 nM. Fast response time, high sensitivity and
ease of preparation method without using any specific electron transfer mediator or specific reagent
are the advantages of the sensor. The modified electrode was applied to the determination of
buprenorphine in human biological fluid at micromolar level without any pretreatment or
separation step.