شماره ركورد كنفرانس :
4046
عنوان مقاله :
KF/HNTS CATALYZED ONE-POT THREE-COMPONENT BIGINELLI REACTIONS: AN EFFICIENT SYNTHESIS OF 3,4-DIHYDROPYRIMIDIN-2-(1H)-ONE
عنوان به زبان ديگر :
KF/HNTS CATALYZED ONE-POT THREE-COMPONENT BIGINELLI REACTIONS: AN EFFICIENT SYNTHESIS OF 3,4-DIHYDROPYRIMIDIN-2-(1H)-ONE
پديدآورندگان :
Ghanei Mercedeh mercedeh_25@yahoo.com Islamic Azad University , Khalilzadeh Mohammad Ali m.khalilzadeh@hotmail.com Qaemshahr Branch, Islamic Azad University , Mahmoodi Hashemi Mohammah mhashemi@sharif.edu Islamic Azad University , Yavari Issa yavarisa@modares.ac.ir Islamic Azad University
كليدواژه :
Biginelli reaction , KF , HNTs , 3,4 , dihydropyrimidin , 2(1H) , ones , multicomponent reaction , solid base catalyst.
عنوان كنفرانس :
چهارمين كنفرانس بين المللي نوآوري هاي اخير در شيمي و مهندسي شيمي
چكيده فارسي :
Potassium fluoride/Holloysite nonotube (KF/HNTs) acts an active hetrogeneos base catalyst for Biginelli reaction. Here we have describe An efficient one-pot synthesis of 3,4- dihydropyrimidine-2(1H)-one via a three-component reaction of aldehyde, urea, and β-ketoester in the presence of a catalytic amount of (KF/HNTs). The experimental results showed that the KF/HNTs had high catalytic activity and it can be recycled without significant loss of activity. This protocols exhibit advantages such as excellent yield, easy work-up and eco-friendly conditions.
چكيده لاتين :
Potassium fluoride/Holloysite nonotube (KF/HNTs) acts an active hetrogeneos base catalyst for Biginelli reaction. Here we have describe An efficient one-pot synthesis of 3,4- dihydropyrimidine-2(1H)-one via a three-component reaction of aldehyde, urea, and β-ketoester in the presence of a catalytic amount of (KF/HNTs). The experimental results showed that the KF/HNTs had high catalytic activity and it can be recycled without significant loss of activity. This protocols exhibit advantages such as excellent yield, easy work-up and eco-friendly conditions.
