Synthesis, Characterization and antibacterial activity of a bis-acylhydrazone Cu(II) complex supported on MSN-APS

According to pore diameter, Porous materials have been classified to microporous (< 2 nm such as zeolites), mesoporous (2-50 nm) and macroporous (50-100 nm) [1]. Zeolites may be had limitations in some applications because of their small dimension [2]. But mesoporous materials are suitable composites at different fields because had proper pore size, high surface area, good distribution, capability for functionalizing surface and stability [3]. M41S are groups of mesoporous silica composites (2-10 nm pore size) including MCM-41, MCM-48 and MCM-50 [4]. Mesoporous silica nanoparticles (MSNs) are MCM-41 composites with particle size under 100 nm [5]. These composites were applied as catalysis, removal heavy metals, drug delivery, enzyme immobilization and etc. [6-8]. At this work we have supported bis-acyl-hydrazone metal complex on MSN-APS. These composites were characterized by several techniques successfully. Antibacterial activity of MSN-APS-complex was investigated against S.aureus and E.coli.