شماره ركورد كنفرانس :
4865
عنوان مقاله :
Electrochemical oxidation of acetaminophen in the presence of metformin
پديدآورندگان :
Bagheri M bagherimaryam466@gmail.com The University of Zanjan , Shayani-Jam H shayan@znu.ac.ir The University of Zanjan , Yaftian M. R yaftian@znu.ac.ir The University of Zanjan
تعداد صفحه :
2
كليدواژه :
Acetaminophen , Metformin , Cyclic voltammetry , Coulometry , Glassy carbon electrodes.
سال انتشار :
1398
عنوان كنفرانس :
بيست و دومين كنفرانس ملي شيمي فيزيك ايران
زبان مدرك :
انگليسي
چكيده فارسي :
In this study, the electrochemical oxidation of acetaminophen in the presence of metformin as an antidiabetic drug in aqueous solution was performed using cyclic voltammetry and controlled potential coulometry techniques. The results show that N-acetyl-P-benzoquinone-imine (NAPQI) obtained from electro-oxidation of acetaminophen has been reacted with metformin via the Michael addition reaction. The mechanism of this reaction was suggested as an ECECC pathway using cyclic voltammetry, controlled-potential coulometry and spectroscopic data. In this work, we introduced new compound with good yields through a catalyst‐free, environmentally friendly method at room temperature under green conditions.
كشور :
ايران
لينک به اين مدرک :
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