شماره ركورد كنفرانس :
3550
عنوان مقاله :
A sensitive colorimetric method for detection of uric acid based on the formation of gold/silver core-shell nanorods
پديدآورندگان :
Nasirloo Elham Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz 5166616471, Iran , Hallaj Tooba v , Amjadi Mohammad amjadi@tabrizu.ac.ir Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz 5166616471, Iran;
تعداد صفحه :
1
كليدواژه :
Au@Ag nanorods , uric acid , surface plasmon resonance , spectrophotometry
سال انتشار :
1397
عنوان كنفرانس :
بيست و پنجمين سمينار ملي شيمي تجزيه انجمن شيمي ايران
زبان مدرك :
انگليسي
چكيده فارسي :
Gold nanorods (Au NRs), as an important class of anisotropic NPs, have received increasing attention in recent years due to their high chemical stability and unique optical properties that is strongly dependent on their size and aspect ratios [1]. In this work, by using Au NRs a simple and sensitive colorimetric method has been developed for detection of uric acid in biological samples. Au NRs were synthesized by a silver ion-assisted seed mediated method and their interaction with uric acid and silver ions was studied. Uric acid can reduce Ag+ to Ag on the surface of Au NRs to form Au core –Ag shell nanorods. This leads to a blue-shift in longitudinal surface plasmon resonance band of Au NRs. The influence of various parameters such as incubation time, pH, concentrations of Au NRs, silver ions and buffer was studied. Based on the correlation of Au NRs LSPR wavelength with the concentration of uric acid, a method for colorimetric determination of uric acid in the concentration range of 0.1-1.0 µM with a detection limit 0.065 µM and RSD of 3.2% was developed. The method was applied for analysis of human plasma and urine samples.
كشور :
ايران
لينک به اين مدرک :
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