Controlled gentamicin delivery via biocompatible system: mesoporous silica nano rods(MSNRs) which capped with zinc sulfide quantom dots(ZnSQDs).

In this project we design a controlled drug delivery system for gentamicin. Gentamicin is a widely used antibiotic for most infections and has a high potential for treating various types of infections. Because of the importance of this drug, we decide to design a green drug delivery system that is be able to get the right amount of drug at the right time to the target tissue. It has been tried to use completely green materials and biocompatible materials for the drug delivery system. The nanosized rods made from silica were selected and, after functionalized the surface of these nanorods, high-yield gentamicin was loaded. Then, loaded nano rods were capped with zinc sulfide quantum dots and release of drug studied as a function of time in stimulated buffer of human fluid body. We use of uv-vis spectrophotometry method to detect gentamicin release amount.