Taşbakan, M S Ege Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey , Deniz, S Ege Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey , Gürgün, A Ege Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey , Başoğlu, Ö Ege Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey , Bacakoğlu, F Ege Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey

Upper gastrointestinal system bleeding in respiratory intensive care unit patients receiving mechanical ventilation

14645

Aim: The aims of this study were to evaluate the frequency, risk factors and outcomes of upper gastro-intestinal system (GIS) bleeding in respiratory intensive care unit (ICU) patients who received mechanical ventilation.Material and Methods: Fifty-six patients (39 males, mean age 64.2±16.6 years), who were treated in the respiratory ICU for more than 5 days were included in the study. Risk factors and clinical outcomes of patients with gastrointestinal bleeding were evaluated.Results: Out of 56 patients, 10 (17.9%) developed upper GIS bleeding and 30 (53.6%) had ventilator associated pneumonia (VAP) and 22 of them (39.3%) died. There was no relationship between stress ulcer prophylaxis, feeding type and upper GIS bleeding, VAP. In patients with upper GIS bleeding, the frequency of VAP was higher (p=0.011), the duration of mechanical ventilation, stay in ICU and hospital were longer (p=0.05, p=0.023 and p=0.038, respectively) and mortality rate was found to be higher (p=0.006). There was no relationship between upper GIS bleeding and disease severity on admission, use of systemic corticosteroid, anti-coagulant therapy and coagulation disorders. Conclusion: Upper GIS bleeding increases the risk of VAP and mortality; prolongs the durations of stay in the ICU and hospital. Therefore, we conclude that upper GIS bleeding is a poor prognostic factor for respiratory ICU patients.

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Respiratory intensive care unit , mechanical ventilation , upper gastrointestinal system bleeding , stress ulcer prophylaxis

Ege Journal Of Medicine

191