Author/Authors :
Ömür, Ö Ege Üniversitesi - Tıp Fakültesi - Nükleer Tıp Anabilim Dalı, Turkey , Akgün, A Ege Üniversitesi - Tıp Fakültesi - Nükleer Tıp Anabilim Dalı, Turkey , Özcan, Z Ege Üniversitesi - Tıp Fakültesi - Nükleer Tıp Anabilim Dalı, Turkey , Çalkavur, I T Ege Üniversitesi - Tıp Fakültesi - Kalp Damar Cerrahisi Anabilim Dalı, Turkey , Yavuzgil, O Ege Üniversitesi - Tıp Fakültesi - Kardiyoloji Anabilim Dalı, Turkey , Özkılıç, H Ege Üniversitesi - Tıp Fakültesi - Nükleer Tıp Anabilim Dalı, Turkey
Abstract :
Aim: In this study, we aimed to research the place of Tc-99m MIBI Gated SPECT used with the sublingual nitrate application in the viability diagnosis.Material and Methods: Fifty patients diagnosed with a coronary artery disease were included in the study. All subjects were evaluated with rest-nitrate Tc-99m MIBI Gated SPECT, echocardiography and angiography. In 50 patients, myocardial perfusion and functional parameters were examined. The five segments myocardial model was used. Results: Normal perfusion was determined in 165 of the 250 segments, there were reversible perfusion defects in 44 and irreversible perfusion defects in 41 segments. If %50 coronary artery narrowness is accepted as significant stenosis, in 59 of the 85 segments in total in which a perfusion defect was detected, we have detected a significant narrowness in the feeding coronary artery. In the myocardial perfusion scintigraphy (MPS) there was not any significant coronary artery stenosis in 105 of the 165 segments with no perfusion defect. When the findings of the Gated SPECT and echocardiography findings were compared, no statistically significant difference was found between the average EF value (43.8+-29.5) calculated with the QPS/QGS programme and the value obtained from the echocardiographic data (46.3+-29.5). In the subjects with irreversible perfusion defects in MPS, the average EF (39.2±9.4) was lower than the general group average (43.8±29.5). LV functional data obtained with Gated SPECT and echocardiography were found compatible in 219 of the 250 segments.Conclusion: We have concluded that Rest-Nitrate Tc-99m MIBI Gated SPECT is a reliable method in viable myocardium research which gives an advantage ın evauatıng LV functions.
