Author/Authors :
Soyer, N Ege Üniversitesi - Tıp Fakültesi - Hematoloji Bilim Dalı, Turkey , Vural, F Ege Üniversitesi - Tıp Fakültesi - Hematoloji Bilim Dalı, Turkey , Dönmez, A Ege Üniversitesi - Tıp Fakültesi - Hematoloji Bilim Dalı, Turkey , Biçeroğlu, S Ege Üniversitesi - Tıp Fakültesi - Radyoloji Anabilim Dalı, Turkey , Tombuloğlu, M Ege Üniversitesi - Tıp Fakültesi - Hematoloji Bilim Dalı, Turkey , Çağırgan, S Ege Üniversitesi - Tıp Fakültesi - Hematoloji Bilim Dalı, Turkey
Abstract :
Geotrichum capitatum infection is a rare, opportunistic fungus which causes invasive disease in immunocompromised patients. We report a case of hepatosplenic infection with Geotrichum capitatum in a patient with acute promyelocytic leukemia. After chemotherapy, the patient developed fever unresponsive to antibiotic treatment, elevated serum alkaline phosphatase. Blood cultures revealed a G. capitatum infection and ultrasound and abdominal computed tomography showed multiple focal lesions in the liver and spleen. We treated the patient successfully with amphotericin B.