Abstract :
Under normal physiological conditions, damaged or aged cells kill themselves by a genetically regulated cell death program called apoptosis (in Greek apo means -far or distant, and ptosis means -to fall off). The process of apoptosis has to be separated from necrosis by different morphological and functional properties. Apoptosis is closely connected to oncogenesis and the cell cycle. Therefore, it is important to study the apoptotic pathways and to show their corporate interaction with the molecular mechanisms of the cell cycle, especially their influence on cell cycle regulation by cyclins, cyclin-dependent kinases and inhibitors. In particular these days where stem cell research reaches its heights, it is indispensable to show cycle characteristics and division capacities of these cells, which the present review tries to resolve.
