مرکز منطقه ای اطلاع رساني علوم و فناوري

Abstract :

There are several definitions for sarcopenia. European Working Group on Sarcopenia in Older People (EWGSOP) defines sarcopenia as “a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength with a risk of adverse outcomes such as physical disability, poor quality of life and death. Additionally, the presence of both low muscle mass + low muscle function (strength or performance) is also recommended as a parameter for the diagnosis of sarcopenia. Intrinsic, multipl extrinsic and behavioral factors (i.e. disuse, physical activity, malnutrition, chronic inflammation and comorbidities) affect the development and/or progression of sarcopenia. There may be interindividual variabilites in the contribution of these factors to the course of the disease. Preventive strategies include primary, secondary, tertiary and quaternary levels. According to the present knowledge, physical exercise and nutrition are the most important elements in all preventive levels. Primary prevention should begin as soon as the underlying process starts. Secondary and tertiary prevention strategies take place in older ages to avoid rapid progression of sarcopenia