SAĞLAMPINAR KARYAĞAR, Sevda Türkiye Cumhuriyeti Sağlık Bakanlığı (TCSB) - Trabzon Kanuni Eğitim ve Araştırma Hastanesi (E A H) - Nükleer Tıp, Türkiye , KARYAĞAR, Savaş Türkiye Cumhuriyeti Sağlık Bakanlığı (TCSB) - Trabzon Kanuni Eğitim ve Araştırma Hastanesi (E A H) - Nükleer Tıp, Türkiye , USLU, Rabia Türkiye Cumhuriyeti Sağlık Bakanlığı (TCSB) - Malatya Beydağı D H - Nükleer Tıp, Türkiye , MÜLAZIMOĞLU, Mehmet Türkiye Cumhuriyeti Sağlık Bakanlığı (TCSB) - Okmeydanı Eğitim ve Araştırma Hastanesi (E A H ) - Nükleer Tıp, Türkiye , ÖZPAÇACI, Tevfik Türkiye Cumhuriyeti Sağlık Bakanlığı (TCSB) - Okmeydanı Eğitim ve Araştırma Hastanesi ( E A H ) - Nükleer Tıp, Türkiye , UYANIK, Ercan Türkiye Cumhuriyeti Sağlık Bakanlığı (TCSB) - Okmeydanı Eğitim ve Araştırma Hastanesi ( E A H ) - Nükleer Tıp, Türkiye

Comparison of the Three Phase Bone Scintigraphy and Tc-99m Ciprofloxacin Scintigraphy in Diagnosis of Septic and Aseptic Loosening of the Hip and Knee Prosthesis

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Objective: In this study, the results of three phase bone scintigraphy and Tc 99m ciprofloxacin scintigraphy were assessed comparatively in the diagnosis of the septic and aseptic loosening of the hip and knee prosthesis. Materials and Methods: Fifty patients who were referred to our clinic with the pre-diagnosis of infection were included in the study. Thirty two of the patients (64%) had hip prosthesis and 18 (36%) had knee prosthesis. Three phase bone scintigraphy and Tc-99m ciprofloxacin scintigraphy were applied at least 3-5 days interval in our clinic. Results: Three phase bone scintigraphy was reported as positive for 23 patients (46%) and negative for 27 patients (54%) in terms of infection. Tc- 99m ciprofloxacin scintigraphy was reported as positive for 19 (54%) and negative for 31 patients (62%). The sensitivity for the three phase bone scintigraphy was found to be 100%. It was 86.6% for the Tc-99m ciprofloxacin scintigraphy. Specificity was 77.5% versus 82.8% (p 0,05); positive predictive value was 65.2% versus 68.4% (p 0,05); negative predictive value was 100% versus 93.5% (p 0,05); accuracy was 84% versus 84% (p 0,05), respectively. Conclusion: Besides being a sensitive method, three phase bone scintigraphy can be used confidently in preventing from the infection existence. Since, the specifity of Tc-99m ciprofloxacin scintigraphy is higher when compared with the three phase bone scintigraphy; the usage of both method in the septic-aseptic loosening sorting is suitable.

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Septic and aseptic loosening , Bone scintigraphy , Ciprofloxacin scintigraphy

Fırat Medical Journal

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