Author/Authors
KÖM, Mustafa Fırat Üniversitesi - Veteriner Fakültesi - Cerrahi Anabilim Dalı, Turkey
Title Of Article
The Efficacy of Hyaluronic Acid/Carboxymethylcellulose Barriers on the Prevention of Postoperative Intraabdominal Adhesions in Rabbits
شماره ركورد
18133
Abstract
Intraabdominal adhesions are one of the common complications seen in abdominopelvic surgery. The purpose of this study was to assess the efficacy of hyaluronic acid/carboxymethylcellulose (HA/CMC) barriers in preventing postoperative intraabdominal adhesions in rabbits. Fourteen rabbits were used in this study. The 2x2 cm part of caecum was meticulously abraded after median laparotomy. The rabbits were divided into the control and experiment groups. No medication was given to the control group. In the experiment group; a 3x3 cm of HA/CMC barrier was covered on the abraded area. Euthenasia was performed on the 14th day postoperative. The results of macroscopic evaluation showed that adhesion scores in the experiment group were found lower than in the control group (P 0.05). Histopathologically, fibrosis and inflammation in the treatment group were lower compared to the control group (P 0.05). In conclusion; HA/CMC barriers were significantly effective in the prevention of postoperative intraabdominal adhesions in rabbits.
From Page
75
NaturalLanguageKeyword
Intraabdominal adhesion , hyaluronic acid , carboxymethylcellulose , rabbit.
JournalTitle
Fırat University Veterinary Journal Of Health Sciences
To Page
79
JournalTitle
Fırat University Veterinary Journal Of Health Sciences
Link To Document