Author/Authors :
Sapkal, Sandip International Bibliography of the Social Sciences (IBSS) - College of Pharmacy - Pharmaceutics, India , Narkhede, Mahesh International Bibliography of the Social Sciences (IBSS) - College of Pharmacy - Pharmaceutics, India , Babhulkar, Mukesh International Bibliography of the Social Sciences (IBSS) - College of Pharmacy - Pharmaceutics, India , Mehetre, Gautam International Bibliography of the Social Sciences (IBSS) - College of Pharmacy - Pharmaceutics, India , Rathi, Ashish International Bibliography of the Social Sciences (IBSS) - College of Pharmacy - Pharmaceutics, India
Abstract :
Natural polymers and its modified forms can be used as best alternative for improving bioavailability of poorly water soluble drugs in solid dispersion. Most of the natural polymers are hydrophilic and having high swelling capacity. Recent trend towards the use of natural polymer demands the replacement of synthetic additives with natural ones. Many plant derived natural polymers are studied for use in solid dispersion systems, out of which natural gums, cyclodextrin and carbohydrate are most extensively studied and used. This review discusses about the majority of these natural polymers, its uses and some recent investigations about modification of natural polymer in solid dispersion systems.
NaturalLanguageKeyword :
Modified natural gum , carbohydrate , dissolution enhancement , solid dispersion
