Balta, ilknur Gulhane Askeri Tip Akademisi - Kecioren Egitim Ve Arastirma Hastanesi, Dermatoloji Klinigi - Kardiyoloji Anabilim Dali, Turkey , Balta, Sevket Gulhane Askeri Tip Akademisi - Kardiyoloji Anabilim Dali, Turkey , Demirkol, Sait Gulhane Askeri Tip Akademisi - Kardiyoloji Anabilim Dali, Turkey

Cardiovascular comorbidities in patients with psoriasis

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Psoriasis is a chronic infammatory disease that affects approximately 1-3% of the population. Psoriasis is associated with conventional cardiovascular risk factors, including hypertension, diabetes mellitus, obesity, smoking and hyperlipidaemia. Furthermore, psoriasis, like other type 1 helper T-cell-driven infammatory disorders such as rheumatoid arthritis and systemic lupus erythromatosus, is an independent risk factor for atherothrombotic disease. Because of psoriasis and atherosclerosis are both characterized by T helper 1 and T helper type 17 activation and reduced T regulatory cell function. Therefore, psoriasis is associated with increased risk of adverse cardiovascular events. Young age, severe skin affection and/ or psoriatic arthritis carry the most risk. The high-risk group of patients with psoriasis may be candidates for early cardiovascular risk factor modiication.

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Psoriasis , cardiovascular , comorbidity

Gulhane Medical Journal

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