Author/Authors :
Eyoh, Agnes B. University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Eyoh, Agnes B. Centers for the Study and Control of Communicable Diseases, Cameroon , Toukam, Michel University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Gonsu, Hortense University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Fokunang, Charles University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Atashili, Julius Centers for the Study and Control of Communicable Diseases, Cameroon , Lyonga, Emilia E. Centers for the Study and Control of Communicable Diseases, Cameroon , Lyonga, Emilia E. University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Ikomey, George University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Ikomey, George Centers for the Study and Control of Communicable Diseases, Cameroon , Mukwele, Bertha Centers for the Study and Control of Communicable Diseases, Cameroon , Mesembe, Martha Centers for the Study and Control of Communicable Diseases, Cameroon , Tsague, Nguefack University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Mandi, Henshaw University of Buea - Department of Health Sciences, Cameroon , Assoumou, Marie Claire Okomo University of Yaounde I - Faculty of Medicine and Biomedical Sciences - Department of Microbiology, Hematology, Parasitology, Immunology and infectious diseases, Cameroon , Assoumou, Marie Claire Okomo Centers for the Study and Control of Communicable Diseases, Cameroon
Abstract :
PURPOSE / AIM Hospital personnel are often colonized with resistant strains of Staphylococcus aureus (SA). These strains could be transmitted to patients, complicating treatment options particularly in resource-limited areas where antimicrobial susceptibility assessment is not systematic. In view of guiding empiric treatment in such patients, we assessed antimicrobial susceptibility profile of Staphylococcus aaureus isolated from the anterior nares of hospital personnel of three health institutions in Yaounde, Cameroon in a cross sectional study. We also assessed risk factors associated with the presence of Methicillin Resistant Staphylococcus aureus (MRSA). METHODS The antibiotic susceptibility profile of fifty eight Staphylococcus aureus strains isolated from hospital personnel to sixteen commonly used antibiotics was assessed using the Kirby Bauer disk diffusion method. Methicillin resistant strains were determined by the Oxacillin Minimum Inhibitory concentration technique. RESULTS All the isolates were resistant to penicillin, ampicillin, and amikacin. No resistance was recorded for netilmicin, vancomycin, and low for gentamicin, rifampin and cephalotin. Eight (13.8%) of the isolates were found to be MRSA. We found 85% of MRSA to be resistant to more than six of the tested antibiotics. No association was found between demographic variables or personal habits and nasal colonization with methicillin-resistant strains. CONCLUSION A relatively high proportion of Staphylococcus aureus isolates in this study were resistant to commonly used antibiotics. This calls for regular monitoring of susceptibility patterns.
