Author/Authors :
Nguefack, S Yaoundé Gynaeco-obstetric and pediatric hospital - Pediatric neurology Unit, Cameroon , Nguefack, S University of Yaoundé I - Faculty of Medecine and biomedical sciences, Cameroon , Ngoh, R University of Yaoundé I - Faculty of Medecine and biomedical sciences, Cameroon , Demanou, M Centre Pasteur du Cameroun - Virology laboratory, Cameroun , Chiabi, A University of Yaounde I - Faculty of Medicine and Biomedical Sciences, Cameroon , Chiabi, A Yaoundé Gynaeco-obstetric and pediatric hospital - Pediatric neurology Unit, Cameroon , Mah, E Yaoundé Gynaeco-obstetric and pediatric hospital - Pediatric neurology Unit, Cameroon , Mah, E University of Yaoundé I - Faculty of Medecine and biomedical sciences, Cameroon , Mbassi Awa, H University of Yaoundé I - Faculty of Medecine and biomedical sciences, Cameroon , Mbassi Awa, H Chantal Biya Fondation - Mother and Child Center - Pediatric neurology Unit, Cameroon , Mbonda, E Yaoundé Gynaeco-obstetric and pediatric hospital - Pediatric neurology Unit, Cameroon , Mbonda, E University of Yaoundé I - Faculty of Medecine and biomedical sciences, Cameroon
Abstract :
Subacute sclerosing panencephalitis (SSPE) is a rare progressive, invariably fatal long-term complication of measles infection. It can manifest three to ten years after the acute infection. It results from mutation in the measles virus protein, and inappropriate immune response. We report the case of a 12 year old adolescent with no past history of measles; but in whom the diagnosis of SSPE was made on the basis of the clinical presentation, electroencephalogram results and the detection of anti measles antibodies in cerebrospinal fluid. SSPE should therefore be considered, in a patient with cognitive impairment and myoclonus in a context where measles is not rare even in the absence of history of measles.
NaturalLanguageKeyword :
Subacute sclerosing panencephalitis , measles , myoclonic jerks , electroencephalogram , anti measles antibodies
