مرکز منطقه ای اطلاع رساني علوم و فناوري - Platelet parameters in pre-eclamptic pregnancies

Author/Authors :

Sezer, Selda Demircan Adnan Menderes Üniversitesi - Tıp Fakültesi - Kadın Hastalıkları ve Doğum AD, Turkey , Küçük, Mert Adnan Menderes Üniversitesi - Tıp Fakültesi - Kadın Hastalıkları ve Doğum AD, Turkey , Yüksel, Hasan Adnan Menderes Üniversitesi - Tıp Fakültesi - Kadın Hastalıkları ve Doğum AD, Turkey , Odabaşı, Ali Rıza Adnan Menderes Üniversitesi - Tıp Fakültesi - Kadın Hastalıkları ve Doğum AD, Turkey

Abstract :

Aim: The aim of this study was to evaluate the platelet parameters in pre-eclamptic and normal pregnant women. Material and methods: Sixty pre-eclamptic women and 75 healthy pregnant women as the control group were enrolled to this retrospective study. The platelet count, mean platelet volume (MPV), platelet crit (PCT) and platelet distribution width (PDW) of the groups were compared. Independent sample t-test was used to compare the parameters between two groups. Results: The mean age of the pre-eclamptic group was 29.2±5.6 and the control group was 28.9±4.5. There was no statistically signifi cant difference between the two groups in terms of the age and gestational weeks (P 0.05). The mean platelet count (x103/μL) was 225,5±88,8 in the pre-eclamptic group and 231,7±45,8 in the control group and there was no statistically signifi cant difference between the groups (P 0.05). The mean value of PCT was 0.20±0.08 in the pre-eclamptic group and 0.20±0.04 in the control group, and there was no signifi cant difference between two groups (P 0.05). It was found that the mean MPV value of the pre-eclamptic group was higher than the control group (9,6±1.6 vs 8.8±1.2, respectively) and there was a statistically signifi cant difference between the groups (P=0.012). The mean PDW value of the pre-eclamptic group and the control group were 17.1±0.8 vs 18.7±1.2, respectively, and there was no statistically signifi cant difference between the groups (P 0,05). Conclusion: The mean value of MPV was higher in the pre-eclamptic group than the control group. However, the mean platelet count, mean values of PCT and PDW of the pre-eclamptic and normal pregnant women were similar.