Arıtürk, Zuhal Dicle Üniversitesi - Tıp Fakültesi - Kardiyoloji Anabilim Dalı, Turkey , Abakay, Abdurrahman Dicle Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey , Tekbaş, Ebru Dicle Üniversitesi - Tıp Fakültesi - Kardiyoloji Anabilim Dalı, Turkey , Çil, Habib Dicle Üniversitesi - Tıp Fakültesi - Kardiyoloji Anabilim Dalı, Turkey , Kırbaş, Gökhan Dicle Üniversitesi - Tıp Fakültesi - Göğüs Hastalıkları Anabilim Dalı, Turkey , Alan, Sait Dicle Üniversitesi - Tıp Fakültesi - Kardiyoloji Anabilim Dalı, Turkey , Yazıcı, Mehmet Dicle Üniversitesi - Tıp Fakültesi - Kardiyoloji Anabilim Dalı, Turkey

The role of the Syndrome X in the pathophysiology of sleep-apnea syndrome

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Objective: Syndrome X or microvascular angina pectoris is defined as angina pectoris due to coronary microvascular dysfunction in patients with non-stenotik epicardial arteries. The aim of his study was to investigate the relationship between obstructive sleep apnea syndrome (OSAS) and syndrome X. Materials and methods: Twenty patients (11 male, 9 female) with the complaint of chest pain who referred to Cardiology Clinics of Dicle University were enrolled in the study as Group 1. All of the patients’ exercise tests were positive, epicardial coronary arteries were normal and coronary flows were slow in Group 1. Thirty healthy person were enrolled in the study as group 2. Polysomnography (PSG) and echocardiography (ECHO) was performed in all patients. Results: In Group 1, 11 (55%) patients had obstructive sleep apnea. In Group 2, three patients (10%) had OSAS. There were significant differences in terms of OSAS frequency among groups. There were no significant differences in terms of left ventricular ejection fraction (LVEF), left ventricular end-systolic diameter (LVESD), left ventricular end diastolic diameter (LVEDD), stroke volume, deceleration time (DT) , ejection time (ET) and the left atrium (LA) diameter between Syndrome X and control groups according to echocardiographic examination (p 0.05). However, IVRT, RA diameter, the myocardial performance index (MPI), PAP, and MEV / mav rates were significantly different (p 0.05). Conclusion: OSAS -also known to cause cardiovascular complications- incidence was significantly higher in patients with syndrome X than the healthy subjects. In OSAS patients, apnea hypopnea index, cardiovascular risk factors such as hypertension and dyslipidemia were more common than healthy subjects. Therefore, these patients should be followed up closely and be treated properly.

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Syndrome X , Obstructive sleep apnea syndrome , Echocardiography

Dicle Medical Journal

362