Bali, Nihat Dicle Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , Karaman, Haktan Dicle Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , Tüfek, Adnan Dicle Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , Kavak, Gönül Ölmez Dicle Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , Yıldırım, Zeynep Baysal Dicle Üniversitesi - Tıp Fakültesi - Anesteziyoloji ve Reanimasyon Anabilim Dalı, Turkey , Cengiz, Mustafa Alman Hastanesi - Anesteziyoloji Birimi, Turkey

Comparison of the efficacy of intrathecally administered levobupivacaine and bupivacaine in pre-eclamptic pregnant women

26426

Objectives: The aim of this study was to compare the efficacy and side effects of levobupivacaine and bupivacaine in pre-eclamptic patients that will undergo caesarean section by spinal anesthesia. Materials and methods: Preeclamptic, 18-45 years-old patients that will undergo a caesarean section were included in the study in a prospective randomized manner. They were separated into two groups: Group B, intrathecally received 2 mL 0.5% bupivacaine (10 mg), while Group L intrathecally received 2 mL 0.5% levobupivacaine (10 mg). Blood pressure and heart rates of the patients were measured and recorded at 3, 6, 9, 12, 15th minutes and thereafter, every 5 minutes during operation. The evaluations were done through the comparison of patient’s and surgeon’s satisfaction between the groups. Visual analog score (VAS) was used for comparison. Results: Systolic arterial pressure values at 3, 15, 35 and 40th minutes in Group B were significantly lower than those in Group R (p 0.05), no significant difference was found in heart rates. Group B more frequently developed hypotension (10 patients versus 15 patients), so significantly greater amount efedrin was needed to treat hypotension (p=0.012). Patient satisfaction was recorded high in favor of Group L (p=0.011), however no difference was found in surgeon satisfaction between two groups (p 0.05). Conclusion: Intrathecal levobupivacaine for spinal anesthesia ensured a more stable hemodynamics but both local anesthesia enabled a sufficient and adequate surgical anesthesia in pre-eclamptic patients.

19

Pre , eclampsia , spinal anesthesia , bupivacaine , levobupivacaine

Dicle Medical Journal

25