Author/Authors :
Yeniova, Abdullah Özgür Keçiören Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Nazlıgül, Yaşar Keçiören Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Çağlar, Feride Keçiören Eğitim ve Araştırma Hastanesi - Dahiliye Klinikleri, Turkey , Kefeli, Ayşe Keçiören Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Küçükazman, Metin Keçiören Eğitim ve Araştırma Hastanesi - Gastroenteroloji Kliniği, Turkey , Şimşek, Gülçin Keçiören Eğitim ve Araştırma Hastanesi - Patoloji Laboratuvarı, Turkey
Abstract :
Eosinophilic gastroenteritis (EG) is a rare disease that is characterized by an eosinophil-driven inflammation of the digestive tract, presenting with gastrointestinal symptoms. In this report, a case of EG in an elderly man who presented with diarrhea was presented. A 68-year-old man admitted to hospital due to diarrhea, nausea, abdominal pain, and weight loss started two weeks ago. Hypereosinophilia were determined. Serum immunoglobulin E level was high. Stool examinations for intestinal parasites were negative. Biopsies were taken from esophagus, stomach, duodenum during upper and lower gastrointestinal endoscopies. Histopathological assessement showed an intense edema, eosinophilic and increased lymphoplasmasitic infiltration in lamina propria. Increased eosinophil count seen in bone-marrow biopsy, atypical cell was not seen. Eosinophilic gastroenteritis was considered and, ketotifen 2 mg/day and methylprednisolone 1 mg/kg/day were started. His symptoms were improved. Gastrointestinal symptoms of EG are nonspecific. The increase of eosinophilic cells in the circulating blood can suggest the possibility of EG. Definite diagnosis is made by histopathological assessment. Glucucorticoid therapy is the mainstay and is effective in the treatment of EG. However, the antihistamines are also used solely or combined with glucocorticoids.
