Author/Authors :
Yalçın, Kadir Serkan Fatih University - Medical School - Department of Internal Medicine, Turkey , Tahtacı, Gözde Fatih University - Medical School - Department of Hematology, Turkey , Balçık, Özlem Şahin Fatih University - Medical School - Department of Hematology, Turkey
Title Of Article :
Role of platelets in inflammation
Abstract :
Inflammation, which is extremely useful process for human body is the response of living vascular tissues to pathological phenomena that removes the pathogens and initiates the healing procedure. Microorganisms, physical trauma, chemical, mechanical, irradiation, or thermal injury, ischemia and immune reactions are most common causes of this exceptionally important event for human body. Platelets are non-nucleated cells in blood that produced in bone marrow as derived from megakaryocytes. Apart from stop bleeding and achieving hemostasis there are incredibly important roles of platelets in inflammation. Platelets contain important mediators for inflammation like neutrophils or macrophages and can alter the course of mechanism. In this article changing platelet function in inflammation and the effect of these functions to the process of inflammation will be discussed.
NaturalLanguageKeyword :
Platelet , inflammation , cytokines
JournalTitle :
Dicle Medical Journal
