Author/Authors :
Altunhan, Hüseyin İzzet Baysal Üniversitesi - Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları AD - Neonatoloji Bilimdalı, Turkey , Annagür, Ali Selçuk Üniversitesi - Selçuklu Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları AD, Neonatoloji Bilimdalı, Turkey , Konak, Murat Necmettin Erbakan Üniversitesi - Meram Tıp Fakültesi - Neonatoloji Bilim Dalları, Turkey , Ertuğrul, Sabahattin Necmettin Erbakan Üniversitesi - Meram Tıp Fakültesi - Neonatoloji Bilim Dalı, Turkey , Yüksekkaya, Hasan Ali Necmettin Erbakan Üniv. - Meram Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları AD Çocuk Gastroenteroloji BD, Türkiye , Örs, Rahmi Necmettin Erbakan Üniversitesi - Meram Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları AD - Neonatoloji Bilimdalı, Turkey
Abstract :
Classical galactosemia is a rarely seen carbohydrate metabolism disorder. The frequency of sepsis significantly increases in patients with galactosemia. The most common agent causing sepsis is E. coli. Sepsis due to fungus in patients with galactosemia is rarely reported. Candida is an important cause of sepsis in newborn intensive care units especially in newborns with underlying risk factors such as prematurity and low birth weight. Although the most common etiologic agent of sepsis is E. coli in cases with galactosemia, it should be kept in mind that candida may also be causative agent of sepsis and meningitis in these patients even though there is no underlying risk factor. Also the clinical and laboratory findings of candidiasis may be obscure. For this reason, especially in newborn candida meningitis, the index of suspicion should be kept high for early diagnosis and treatment. In such patients cerebrospinal fluid analysis, culture and brain imaging should be done necessarily, because early diagnosis and treatment will be life saving. In this article we reported a galactosemia case with the diagnosis of meningitis and Candida albicans grown in his blood culture derived on the fourth day of admission to clinic.
NaturalLanguageKeyword :
Candida albicans , galactosemia , meningitis , newborn , sepsis