Author/Authors :
Ece, Aydın Dicle Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Türkiye , Güneş, Ali Dicle Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Türkiye , Tan, İlhan Dicle Üniversitesi - Tıp Fakültesi - Çocuk Hastalıkları Anabilim Dalı, Türkiye , Uluca, Ünal Dicle Üniversitesi - Tıp Fakültesi - Çocuk Hastalıkları Anabilim Dalı, Türkiye , Kelekçi, Selvi Dicle Üniversitesi - Tıp Fakültesi - Çocuk Hastalıkları Anabilim Dalı, Türkiye , Yel, Servet Dicle Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Türkiye , Şen, Velat Dicle Üniversitesi - Tıp Fakültesi - Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Türkiye
Abstract :
Objective: Kawasaki disease is a vasculitis that rarely diagnosed in our country. In this study, it was aimed to evaluate clinical and laboratory findings and outcome in 13 children with Kawasaki disease. Materials and methods: Diagnosis of Kawasaki disease was done based on its diagnostic criteria. Biochemical tests and complete blood count were performed and acute phase reactants were measured. Urinalysis and infection investigations were also done. Echocardiography was performed to all patients. Intravenous immunoglobulin (IVIG, 2 g/kg) was given and acetylsalicylic acid (100 mg/kg) was started to all patients. Results: Eight male and 5 female children were included. The mean age 3.3±1.6 years (range 1.5-7) and 12 children were under 5 years of age. The mean diagnosis delay duration was 14.2±10.6 days, median 14 days (range, 6-35) before admission to our hospital. There was high fever in all patients, rash on body in 11/13 patients, lymphadenopathy in 9/13, desquamation at hand and feet in 5/13, conjunctivitis and oral mucosal changes in 5/11. Arthritis was found in 5/13, and convulsion and respiratory distress in one each. Dilatation was found in main coronary artery in 5/13 patients by echocardiography. Intravenous immunoglobulin (IVIG) and acetylsalicylic acid were given to all patients. Fever and other clinical and laboratory abnormalities were healed in patients; however, coronary artery dilatation was persisted in two patients despite IVIG treatment. Conclusion: Diagnostic delay was frequently in Kawasaki disease due to rarity of the disease and coronary artery dilatation may not be healed always.
NaturalLanguageKeyword :
Kawasaki disease , fever , vasculitis , coronary artery dilatation , IVIG treatment
