Author/Authors :
Doğan, Mustafa Namık Kemal Üniversitesi - Tıp Fakültesi - Enfeksiyon Hastalıkları AD, Türkiye , Güneş, Hayati Namık Kemal Üniversitesi - Tıp Fakültesi - Tıbbi Mikrobiyoloji AD, Türkiye , Mete, Rafet Namık Kemal Üniversitesi - Tıp Fakültesi İç Hastalıkları AD - Gastroenteroloji BD, Türkiye , Taş, Tekin Abant İzzet Baysal Üniversitesi - Tıp Fakültesi - Tıbbi Mikrobiyoloji AD, Türkiye , Mengeloğlu, Fırat Zafer Abant İzzet Baysal Üniversitesi - Tıp Fakültesi - Tıbbi Mikrobiyoloji AD, Türkiye , Küçükbayrak, Abdulkadir Abant Izzet Baysal Üniversitesi - Tip Fakültesi - Enfeksiyon Hastaliklari AD, Turkey
Abstract :
Objective: In this study, it is aimed to evaluate the correlation of the test results of anti-HDV and HDAg in patients with chronic HBV infection and to collect data concerning HDV epidemiology. Materials and methods: Anti-HDV and HDAg test results and demographic data of the patients with chronic HBV infection by gastroenterology and infectious diseases in Agri State Hospital between January 2009-May 2012 were analyzed retrospectively. HBsAg and Anti-HBc IgM tests were performed with macroelisa, anti-HDV and HDAg were tested with microelisa. Results: A total of 787 patients constituting 315(40.0%) females and 472(60.0%) males were included in the study. All the patients were HBsAg positive and Anti-HBc IgM negative. Of these patients, 55(7.0%) cases were only anti-HDV positive; 19(2.4%) were only HDAg positive and two cases were both anti-HDV and HDAg positive. A total of 76(9.7%) patients had positive findings of HDV infection. The mean age of HDV-positive patients was 42.1±15.2 (11-77 years); of these 36(47.4) were female and 40(52.6) were male. Conclusion: In patients with chronic viral hepatitis, HDV infection still remains significant. In our study HDV infection rate was detected as 9.7%. Although this rate is lower than the earlier reports of the same region, it is above the national average.
NaturalLanguageKeyword :
HDV , HDAg , delta antigen , anti , HDV , chronic hepatitis B , pain
