Çatak, Onur Elazığ Eğitim ve Araştırma Hastanesi - Göz Hastalıkları Bölümü, Türkiye , Aydemir, Orhan Fırat Üniversitesi - Tıp Fakültesi - Göz Hastalıkları Anabilim Dalı, TÜRKİYE , Üstündağ, Bilal Fırat Üniversitesi - Biyokimya Anabilim Dalı, Türkiye

Tear levels of IL-16 in vernal keratoconjunctivitis

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Objective: Vernal keratoconjunctivitis is more common in children and young adults having an atopic background. The aim of the present study was to determine the interleukin-16 (IL-16) levels in tear fluids of patients with vernal keratoconjunctivitis (VKC). Methods: Tear fluid samples were collected from 20 patients with VKC and 10 healthy subjects. Tear fluid samples were collected with microcapillary tubes for hematocrit at the lateral canthus of patients in the supine position without any anesthesia. Tear levels of IL-16 were measured by ELISA kit. Results: The mean levels of IL-16 among the patients (514±135 pg/ml) was significantly higher than among controls (358±139 pg/ml) (p=0.04). Conclusions: These results considered that IL-16 have significant effect on the pathogenetic process of vernal keratoconjunctivitis.

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Interleukin , 16 , vernal keratoconjunctivitis , enzyme , linked immunosorbent assay

Dicle Medical Journal

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