Author/Authors :
Dertlioğlu, Selma Bakar Fırat Üniversitesi - Tıp Fakültesi - Dermatoloji AD, Türkiye , Demir, Betül Elazığ Eğitim ve Araştırma Hastanesi - Dermatoloji Kliniği, Türkiye , Karaoğlu, Aziz Dokuz Eylül Üniversitesi - Tıp Fakültesi - Onkoloji Enstitüsü Tıbbi Onkoloji BD, Türkiye , Uçak, Haydar Dicle Üniversitesi - Tıp Fakültesi - Dermatoloji Anabilim Dalı, TÜRKİYE
Abstract :
Objective: The aim of this study is to investigate skin findings in patients with internal malignancy and highlight the primary skin problems in these cases. Methods: In this study, the findings of cutaneous of 200 patients, hospitalized in the Department of Oncology Fırat University Hospital, were evaluated. The medical histories provided by the patients were recorded, comprehensive cutaneous and systemic examinations were performed, and clinical photos were taken. When considered necessary, skin biopsy and scrapings for fungal infections were collected, while all the cutaneous metastatic lesions were confirmed by histopathology. Results: Among the 200 inpatients with internal malignancy who were admitted to the Department of Oncology, 88 (44%) were female and 112 (56%) were male. Eighty-three patients (41.5%) had hair findings, while hair involvement was found to have a significant relationship with chemotherapy (p=0.001), number of cycles (p=0.001), and radiotherapy (p=0.04). As 119 patients (59.5%) exhibited nail findings, nail involvement was found to be linked with chemotherapy (p=0.001) and number of cycles (p=0.05). Oral mucosa involvement was observed in 100 patients (50%) and palmoplantar involvement was determined in 132 patients (66%); both were significantly associated with chemotherapy (p 0.05). Conclusion: As well as skin metastases, internal malignancy cases accompany with many hair, nail, skin, and mucosal findings, which are significantly associated with chemotherapy and the number of its cycles.
