Author/Authors :
Gencer, Baran Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Göz Hastalıkları AD, Türkiye , Güneş, Fahri Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Hastalıkları AB Dalı, Türkiye , Tan, Yusuf Ziya Çanakkale 18 Mart University - Medical Faculty - Nuclear Medicine, Turkey , Akbal, Erdem Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Hastalıkları AB Dalı, Türkiye , Tufan, Hasan Ali Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Göz Hastalıkları AB Dalı, Türkiye , Ekim, Yeliz Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Göz Hastalıkları AB Dalı, Türkiye , Şen, Hacer Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Hastalıkları AB Dalı, Türkiye , Çömez, Arzu Taşkıran Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Hastalıkları AB Dalı, Türkiye , Özdemir, Semra Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Nükleer Tıp AB Dalı, Türkiye , Kara, Selçuk Çanakkale Onsekiz Mart Üniversitesi - Tıp Fakültesi - Göz Hastalıkları AB Dalı, Türkiye
Abstract :
Objective: High prevalence of Helicobacter pylori (HP) in the glaucoma patients was shown in recent studies. In our prospective study we aimed to compare the intraocular pressure (IOP) and the retinal nerve fiber layer thickness (RNFLT) in patients with HP positive and negative. Methods: In 91 patients with gastritis HP was investigated by urea breath test (UBT) and biopsy sample culture Following the full ophthalmologic examination the patients’ IOP was measured by Goldmann applanation tonometry and RNFLT was measured by spectral optic coherence tomography. The patients’ demographic and clinical characteristics were compared with the χ² test for categorical variables and with the Mann Whitney U test for continuous variables. Results: Of the 90 patients who meet the including criteria, HP was detected in 74 patients (27 male, 47 female) positive, and in 16 patients (7 male, 9 female) negative. Median (minimum-maximum) age values were 46 (18-79) in HP positive group and 51 (18-67) in HP negative group. One hundred forty seven eyes in 74 HP positive patients and 31 eyes in 16 HP negative patients included in the study. Median IOP values were determined 14 (7-21) mmHg in HP positive group and 14 (8-18) mmHg in HP negative group. The measurements of RNFLT in superior, temporal, inferior and nasal quadrants found to be respectively 122(98-165), 68(50-101), 135(93-188), 79(51-120) micron in HP positive group and 120(94-161), 67(43-104), 129(94-166), 76(50-97) micron in HP negative group. No statistically significant difference was found when compared IOP and RNFLT measurements between the two groups (p 0.05). Conclusion: In this study found that the IOP and RNFLT measurements of HP positive group was not show statistically significant difference compared with HP negative group. In a large case series, randomized, case-controlled, histologic and serologic studies should be done to show the relationship between HP and glaucoma.
NaturalLanguageKeyword :
Helicobacter pylori , glaucoma , intraocular pressure , retinal nerve fiber layer thickness.
