Öztürk, Gülfer Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Klinik Biyokimya Bölümü, Türkiye , Bulut, Erdem Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Klinik Biyokimya Bölümü, Türkiye , Akyol, Sümeyya Turgut Ozal University - Vocational School of Health Sciences, Turkey , Akyol, Sümeyya Gaziosmanpaşa Üniversitesi - Tıp Fakültesi - Biyokimya Anabilim Dalı, Türkiye , Taşlıpınar, Mine Yavuz Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Klinik Biyokimya Bölümü, Türkiye , Giniş, Zeynep Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Klinik Biyokimya Bölümü, Türkiye , Uçar, Fatma Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Klinik Biyokimya Bölümü, Türkiye , Erden, Gönül Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi - Klinik Biyokimya Bölümü, Türkiye

The effect of serum 25(OH) vitamin D on hemogram parameters

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Objective: Vitamin D that has pleiotropic hormone characteristics is a fat soluble vitamin. In general, vitamin D is known to be associated with rickets, but the studies show that vitamin D also acts on tissues and cells other than bone itself. In this study, we aimed to investigate if vitamin D has any effects on hemogram parameters or not. Methods: This retrospective study was done with the data obtained from 243 female and 59, totally 302 patients. Vitamin D level and hemogram parameters [(red blood cell (RBC), hemoglobin (Hb), white blood cell (WBC), platelet (PLT), mean platelet volume (MPV), and red cell distribution width (RDW)] of patients were obtained. Patients were divided into 4 groups according to their levels of vitamin D: Group 1: 10 ng/mL; Group 2: 10-19 ng/mL; Group 3: 20-29 ng/mL, and Group 4: 30-60 ng/mL. Results: There were no significant differences in RBC, Hb, WBC, PLT, MPV, and RDW between the groups (p 0.05). Also, there was no correlation between the hemogram parameters and vitamin D.Conclusion: According to the literature, there are a lot of studies that show the relationship between vitamin D and WBC, RBC, and PLT. However, contrary to the previous studies, we were unable to find any significant relationship between vitamin D and hemogram parameters. These results serve the idea that the effects of vitamin D on the hematopoietic system should be further investigated experimentally and clinically.

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Vitamin D , WBC , RBC , PLT , Hemoglobin.

Dicle Medical Journal

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