Author/Authors :
İçer, Mustafa Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey , Zengin, Yılmaz Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey , Gündüz, Ercan Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey , Durgun, Hasan Mansur Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey , Orak, Murat Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey , Üstündağ, Mehmet Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey , Güloğlu, Cahfer Dicle University - Faculty of Medicine - Department of Emergency Medicine, Turkey
Abstract :
Toxic epidermal necrolysis (TEN) is a rare, life-threatening condition that is usually associated with medication use and characterized by separation of epidermis and dermis and a scalded skin appearance. A 71-year-old man presented to emergency department with fever, malaise, and hyperemic skin eruptions and bullae. Skin lesions covered more than 70% of total body surface area. Nikolsky sign was positive. He had been begun ceftriaxone for pneumonia before. TEN was considered as the initial diagnosis; the medication he used was stopped, appropriate supportive treatment was begun, and the patient was admitted to intensive care unit. He was discharged on 8th day after skin epithelization occurred. Toxic epidermal necrolysis is a highly fatal syndrome, in which early diagnosis, stopping the offensive drug, and administering appropriate supportive treatment are important components of the management.
