Author/Authors :
şahin, muhammed dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey , şahin, alparslan dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey , kılınç, faruk elazığ eğitim ve araştırma hastanesi - iç hastalıkları endokrin bilimdalı , özkurt, zeynep gürsel dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey , karaalp, ümit dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey , yüksel, harun dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey , türkcü, fatih mehmet dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey , çaça, ihsan dicle üniversitesi - tıp fakültesi - göz hastalıkalrı ad, Turkey
Abstract :
Objective: We aimed to compare the peripapillary retinal nerve fiber layer (pRNFL) and choroidal thickness in naive type 2 diabetic patients without diabetic retinopathy (DR) with healthy subjects.Methods: The study included newly diagnosed diabetic patients without DR and healthy control subjects. Horizontal plane scan of choroid was performed using enhanced depth imaging (EDI) mode of spectral-domain optical coherence tomography (SD-OCT). The choroidal thickness was measured at the central fovea and at 1000 μm nasal and temporal from the center of the fovea. In addition, the same measurements were performed for pRNFL thickness. Results: The study included 28 eyes of the 28 newly diagnosed with diabetic patients without DR and 28 eyes of the 28 healthy subjects. Age, gender, spherical equivalent refraction, best-corrected visual acuity, intraocular pressure and axial length were not difference between groups. The choroidal thickness of subfoveal and temporal areas were thinner in the naive DM group than that of control group (p = 0.04, p = 0.006, respectively.). In pRNFL analysis, average, nasal and superior temporal quadrants were significantly thinner in the newly diagnosed with DM than those of control group. There were no significant differences in other pRNFL quadrants. Conclusion: When the data were analyzed, in addition to thinning of the choroid layer, it is possible to say that some thinning can be observed in the pRNFL particularly at the average, nasal and temporal superior quadrants in the patients newly diagnosed with DM without DR.
