Coskun, Melike University of Afyon Kocatepe, A.N.S Campus - Faculty of Veterinary Medicine - Department of Surgery, TURKEY , Saritas, Z. Kadir University of Afyon Kocatepe, A.N.S Campus - Faculty of Veterinary Medicine - Department of Surgery, TURKEY

Comparison of the Effects of Sevoflurane and Isoflurane Anaesthesia on Intraocular Pressure in Dogs

32945

This study aimed to compare the effects of sevoflurane and isoflurane on intraocular pressure (IOP) in dogs. The study animals were 12 healthy dogs of diverse age (1-4 years), sex and breed. The dogs were divided into two groups. The first (SEVO group, n = 6) was received anesthesia with atropine sulfate, xylazine hydrochloride (HCI), thiopental sodium and sevoflurane. Anesthesia in the second group (ISO group, n = 6) was carried out with isoflurane instead of sevoflurane, administered with the same doses of the same other drugs. IOP was measured by Schiotz tonometer with 5.5 g, 7.5 g or 10 g weights.The obtained values were interpreted through to the calibration table of Peiffer and Friedenwald.The decrease in IOP was smaller in the SEVO group as compared to ISO. A decline in IOP during the maintenance phase was seen in both groups up to 60 minutes.The decrease in the ISO group was statistically significant (P 0.0001), however, while this was not the case in the SEVO group. An IOP increase was recorded 60 min after the anesthesia, while the finding on the first day was similar to that at the start of anesthesia maintenance. In this study, sevoflurane anesthesia was found to be safer than the one with isoflurane with regard to IOP and the examined hemodynamic parameters.

7

Cardiac Index , Central Venous Pressure , Dog , Heart Rate , Intra , Ocular Pressure , Isoflurane , Mean Arterial Pressure , Schiotz Tonometry , Sevoflurane

Kocatepe Veterinary Journal

14