Author/Authors :
Şanlısoy, Fatma Celal Bayar Üniversitesi - Tıp Fakültesi - Tıbbi Biyoloji Anabilim Dalı, Turkey , Altıntaş, Nuray Celal Bayar Üniversitesi - Tıp Fakültesi - Tıbbi Biyoloji Anabilim Dalı, Turkey , Büyükyazı, Gürbüz Celal Bayar Üniversitesi Beden - Eğitimi Spor Yüksek Okulu - Spor Sağlık Bilimleri, Turkey , Candan, Nurullah Celal Bayar Üniversitesi - Beden Eğitimi Spor Yüksek Okulu - Beden Eğitimi ve Spor Öğretimi, Turkey
Abstract :
Aim. The aim of our study is to investigate whether the genetic base of elite athletes in Aegean region have positive effects on their performance in sports by molecular techniques. Methods. Molecular genetic study was applied to the 105 volunteer elite athletes and 105 volunteer control group (sedantery individuals) individuals. Five milliliter blood samples were taken from each volunteer individuals into the tubes containing EDTA. DNA isolation was performed according to the standard protocols. Polymorphism was determined by Polymerase Chain Reaction (PCR) and Restriction Length Polymorphism (RFLP) techniques. The statistical analysis of our study was performed by using SPSS 15.0 program. Results. Significant difference (x2 =17.9; p=0.000) was found in the distribution of RR and RX genotypes between the elite athletes and sedentary individuals (χ2= 17,9; p=0,000). Conclusion. This is the first study in the Aegean region investigating the prevalence of ACTN3 R577X genotype in elite athletes and sedentary individuals. We think that our study will initiate further researches on this subject.
