Şahin, Ali Cumhuriyet University - School of Medicine - Department of Rheumatology, Turkey , Erten, Şükran Yýldýrým Beyazit University - School of Medicine, Atatürk Education and Research Hospital - Department of Rheumatology, Turkey , Şahin, Mehtap Cumhuriyet University - School of Medicine - Department of Biochemistry, Turkey , Koçarslan, Sezen Harran University - School of Medicine - Department of Medical Pathology, Turkey , Türesin, Ahmet Kerim Cumhuriyet University - School of Medicine - Department of Internal Medicine, Turkey

Familial Mediterranean fever (FMF) and Sjogren’s syndrome: A case responding to azathioprine treatment

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Sjögren’s syndrome (SS) is a chronic, autoimmune, systemic exocrinopathy and extraglandular manifestations can be seen in the course of the disease. Vasculitic skin lesions can rarely be seen in patients. Familial Mediterranean fever (FMF) is a familial, recurrent, autoinflammatory disease which is seen mostly in young people and characterized by self-limiting attacks responding to colchicine treatment. However, resistance to colchicine might be seen in some cases. Coexistence of FMF and SS is rare and the use of azathioprine (AZA) for the treatment of resistant FMF is yet controversial. Herein, we aim to share the post-treatment positive findings of a colchicine-resistant patient diagnosed with FMF and SS comorbiding vasculitis treated with AZA.

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azathioprine , resistant , FMF , Sjögren’s syndrome , vasculitis

Cumhuriyet Medical Journal

240