Abstract :
Objective: One of the risk factor for different psychiatric disorders has been indicated as hypovitaminosis D. The present study aimed to compare 25 (OH) D level between 4 different types of psychiatric disorders (schizophrenia, bipolar disorder, depression and anxiety disorder) andhealthy controls, and to assess the risk factors of hypovitaminosis D in psychiatric inpatients.Method: This retrospective study included 974 individuals [depression (n=553), bipolar disorder(n=135), schizophrenia (n=186) and anxiety disorder (n=100)] who received inpatient treatment inpsychiatry clinic between 2012 and 2014, and 574 individuals in control group who were notdiagnosed with a psychiatric condition. A 25 (OH) D level less than 21 ng/mL was considered toindicate hypovitaminosis D. Results: 25 (OH) D level average of the control group was found to be significantly higher than that of the four psychiatric diagnosis groups (p 0.05). There was no significant difference among 25 (OH) D level of psychiatric diagnosis groups (p 0.05). Comparing 25 (OH) D level among age groups in each study group, it was found that 25 (OH) D level of schizophrenic patients with an age range of 35-54 was found to be significantly lower than that of schizophrenic patients with an age range of 18-34 (p 0.05). 25 (OH) D levels by genders were lower among women in all diagnosis groups (p 0.05), while they were similar for both genders in control group (p 0.05). Logistic regression analysis of the study parameters suggested that the female gender (odds ratio: 3.46; 95% confidence interval: 0.99-1.01), winter and spring seasons (odds ratio: 2.56; 95% confidence interval: 1.69-3.86 and odds ratio: 2.03; 95% confidence interval: 1.33-3.11, respectively) were significant predictors in level of vitamin D in psychiatric inpatients. Conclusions: Hypovitaminosis D is a condition that frequently exists in inpatients in psychiatry clinic suffering from schizophrenia, bipolar disorder, anxiety disorder and depression. Being a female, winter and spring are the most remarkable risk factors in these patients.
NaturalLanguageKeyword :
Hypovitaminosis D , schizophrenia , bipolar disorder , depression , anxiety
