Author/Authors :
DİLTEMİZ, Sibel Emir Anadolu Üniversitesi - Fen Fakültesi - Kimya Bölümü, Turkey , ÖZCAN, Ayça Atılır Anadolu Üniversitesi - Fen Fakültesi - Kimya Bölümü, Turkey , YALÇINKAYA, Özlem Anadolu Üniversitesi - Fen Fakültesi - Kimya Bölümü, Turkey
Title Of Article :
DEVELOPMENT OF SENSOR BASED ON REFLECTOMETRIC INTERFERENCE SPECTROSCOPY FOR DETERMINATION OF TNF-α
Abstract :
In this work, sensor system based on reflectometric interference spectroscopy has been prepared for selective recognition and binding of TNF-α biomolecules. For this purpose, carboxymethyldextran coated and reflectometric interference spectroscopy based sensor systems have been activated for binding of suitable orientated antibody. Then, anti-TNF-α antibody has been bound on the surface and binding efficiency and binding constants of prepared sensors have been investigated.
NaturalLanguageKeyword :
TNF , α , Reflectometric interference spectroscopy , Biosensor systems.
JournalTitle :
Anadolu University Journal of Science and Technology. A : Applied Sciences and Engineering
