AVCI, Gülcan Afyon Kocatepe Üniversitesi - Veteriner Fakültesi - Biyokimya AD, Türkiye , KÜÇÜKKURT, İsmail Afyon Kocatepe Üniversitesi - Veteriner Fakültesi - Biyokimya AD, Türkiye , KONTAŞ, Tünay Çankırı Karatekin Üniversitesi - Fen Fakültesi - Kimya Bölümü Biyokimya AD, Türkiye , ERYAVUZ, Abdullah Afyon Kocatepe Üniversitesi - Veteriner Fakültesi - Fizyoloji AD, Türkiye , FİDAN, Fatih Afyon Kocatepe Üniversitesi - Veteriner Fakültesi - Biyokimya AD, Türkiye

Effects of dietary zinc supplemetation on plasma leptin, insulin and thyroid hormones concentration with some biochemical parameters in sheep species

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In the present study, an experiment was designed to investigate how zinc supplementation affect plasma leptin, insulin, total triiodothyronine (T3), thyroxine (T4) and free triiodothyronine (FT3), free thyroxine (FT4) and some biochemical parameters between Akkaraman sheep as fat-tailed breed and Merino sheep as thin-tailed breed. The animals were equally divided into four groups of 24 animals each. Group I (control Akkaraman) and group III (control Merino) were fed with a basis diet (roughages such as alfalfa hay + concentrate feed). Group II (Zn-Akkaraman) and group IV (Zn-Merino) were fed a at 250 mg/kg Zn ( ZnSO4. 7H2O) added to basis diet. The experimental study was lasted for 30 days and blood samples were taken from the animals to determine plasma concentrations of leptin, insulin, free triiodothyronine (FT3), free tetraiodothyronine (FT4), total triiodothyronine (T3), tiroxin (T4), urea, glucose, malondialdehyde (MDA), glutation (GSH), total antioxidant activity (TAA), β-karoten and vitamin A at the end of trial. Both sheep species in the Zn groups had significantly higher plasma Zn values than the controls throughout the experimental period. The levels of plasma leptin, insulin, thyroid hormones, glucose, urea, MDA, GSH, TAA and vitamin A were insignificant changed both Akkaraman and Merino in the Zn groups. However, the concentrations of plasma glucose, urea and β-caroten were higher in Merino control group than those of Akkaraman control group. This results indicated that there was no effect of dietary zinc supplemantation on the plasma leptin, insulin and thyroid hormones and another parameters in both sheep species with different tail types.

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Akkaraman sheep , insulin , leptin , Merino sheep , zinc.

Veterinary Journal of Ankara University

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