Author/Authors :
SARI DOĞAN, Fatma Göztepe Training and Research Hospital - Department of Emergency Medicine, Turkey , DENİZBAŞI ALTINOK, Arzu Marmara University - School of Medicine - Department of Emergency Medicine, Turkey , ECMEL ONUR, Özge Marmara University - School of Medicine - Department of Emergency Medicine, Turkey , GÜNEYSEL, Özlem Lütfü Kırdar Training and Research Hospital - Department of Emergency Medicine, Turkey , AKOĞLU, Haldun Lütfü Kırdar Training and Research Hospital - Department of Emergency Medicine, Turkey
Abstract :
Objectives: Various levels of dysfunction and damage can occur in the central nervous system of patients experiencing seizures. It is known that these impairments can be assessed by measurement of biochemical markers. S100B proteins have been extensively studied in recent years. We have assessed whether there is a change in serum S100B protein levels during seizures which lead to cerebral hypoperfusion and/or hypoxia. Patients and Methods: A total of 56 patients admitted to an emergency service due to seizures and more than 18 years of age were included in the study. The control group consisted of 20 patients who were admitted to the emergency service due to complaints other than seizures. Results: There was a significant difference between the groups in terms of gender, hemoglobin levels and S100B levels, whereas there was no significant difference in terms of glucose, sodium and potassium levels. The S100B levels were significantly lower in the patient group compared to the control group. Hemoglobin levels was significantly lower in the control group compared to the patient group. Conclusion: Serum S100B protein concentration was found to be significantly lower in patients compared to controls.
