Author/Authors :
Turhan, Vedat Gülhane Askeri Tıp Akademisi - Haydarpaşa Eğitim Hastanesi - Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Servisi, Türkiye , Hatipoğlu, Mustafa Gülhane Askeri Tıp Akademisi - Haydarpaşa Eğitim Hastanesi - Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Servisi, Türkiye
Abstract :
Today, leptospirosis is also an important disease for our country which is commonly encountered type of zoonosis throughout the world especially in tropical regions. Leptospirosis can be seen as a natural disasters (earthquakes, tsunami, land sliding, flooding, sudden or heavy rains) associated outbreaks in tropical and plentiful rainy areas. Leptospirosis should be investigated in the occurrence of acute fever together with some occupational activities, recreational activities, or travel infections in both of developed and developing countries. Leptospirosis is an acute infectious disease caused by a spirochete of the pathogenic form leptospira gender. The pathogens are transmitted a lot of infected animal and retain in their kidneys for along time and eliminate them in the urine. Transmission follows contact with fresh water contaminated with the urine of infected animals.Leptospirosis course is vary; ranging from asymptomatic infections to severe in some cases with fatality ranging to 5 to 40 percent together with multiorgan failure (jaundice, liver and renal failures, haemorrhagic diathesis). Leptospirosis tests should be applied to patients who have cardinal symptoms and clinical findings as well as high fever, periorbital/frontal headache, myalgia, conjunctival hyperemia, neutrophilia, increased ALT/AST, increased CPK or thrombocytopenia, urine abnormalities, elevation of urea and creatinine.Leptospirosis-ELISA test is one of the standart methods to perform and more sensitive especially in the first week of the disease. Microagglutination test (MAT) still has a gold standart in the diagnosis of leptospirosis despite it’s complexity to control, perform, and interpret. Preferring of the “rapid and easy to perform tests” like slide agglutination test or urine dipstick tests for leptospirosis diagnosis could be reasonable especially in the leptospirosis outbreaks. Currently, there is a need to development of an effective vaccine for humans and also increase awareness in doctors against to leptospirosis.
NaturalLanguageKeyword :
Leptospirosis , Weil’s disease , Hepatonephritis , Urine abnormalities , Outbreak , CPK , Thrombocytopenia , Renal failure
