Güven, Davut Ondokuz Mayis University - Medical Faculty - Department of Obstetrics and Gynecology, Turkey , Ökten, Gülsen Ondokuz Mayıs University - Medical Faculty - Department of Medical Genetics, Turkey , Koçak, İdris Ondokuz Mayis University - Medical Faculty - Department of Obstetrics and Gynecology, Turkey , Üstün, Cazip Ondokuz Mayis University - Medical Faculty - Department of Obstetrics and Gynecology, Turkey

β-Thalassemia: Early prenatal diagnosis

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A case of beta-thalassemia major diagnosed by fetal DNA analysis on a chorion biopsy during the 11th, week of gestation is described. A 30 year-old Gravida 2, Parite 1 patient whose firstborn died of beta thalassemia major (Cd8/A) when 2 years old, was admitted to our clinic on her 10th week of pregnancy. Chorionic villus sampling was performed and resulted as beta thalassemia major (Cd8/Cd8).

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β , Thalassemia major , Prenatal diagnosis , Thalassemia , Fetal DNA analysis , Chorion biopsy , Genetic defect

Journal Of Experimental an‎d Clinical Medicine

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