Evaluation of Red Cell Distribution Width (RDW) in Patients with Acute Coronary Syndromes

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Objective: The RDW a recently described novel risk marker has been shown to be predictive of morbidity and mortality in variety of cardiovascular settings, and routinely reported as part of the complete blood count. We thought that RDW can increase in patient with ACS and investigated the effect of RDW on the clinical and angiographic classification of ACS. Material and Methods: 236 patients with ACS, 46 patients with heart failure and 136 control patients were included to the study. ACS group divided into four subgroups clinically (stabil AP, unstabil AP, acute MI, non-cardiac AP) and angiographically divided into three subgroups (critical vascular occlusion, non-critical vascular occlusion, normal). The groups were compared according to laboratory parameters. Results: There was difference between heart failure group and the other groups according to levels of total cholesterol, triglyceride, calcium and WBC. There was difference in all groups according to levels urea, creatinine, albumin, neutrophil count, RDW and troponin (p 0.05). In clinical classification, There was no difference in levels of RDW while there was a difference between acute MI group and the others in troponin level (p 0.05). In angiographic evaluation, there was difference between normal group and the others according to levels RDW (p 0.05). Conclusion: We detected that RDW were increased in patients presenting with ACS and heart failure, but we saw no difference between the subtypes of ACS. In conclusion, we think that RDW might be considered with other cardiac markers for the evaluation of ACS patients admitted to emergency departments.

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Acute coronary syndrome , red cell distribution width , troponin

Kocatepe Medical Journal

105

Kocatepe Medical Journal