Premise Factors of Mortality in Acute Kidney Injury

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Objective: Procalcitonin (PCT), C-Reactive Protein, serum amyloid A (SAA) and serum cholesterol values are early markers for inflammation, infection and malnutrition. In development acute kidney injury (AKI) infection, oral intake disorders, dehydratation and malnutrition have important place. These factors are important in the early detection of treatment. Material and Methods: Between January 2013-2014 in our nephrology clinic followed 182 patients and diagnosed AKI with RIFLE (risk, injury, failure, loss, end stage renal failure) and AKIN (acute kidney injury network) criterias. Patients were compared according to nutritional and inflammatory markers with healthy control group (52 patients). Results: Albumin, CRP, procalcitonin and SAA values in AKI patients favor compared with healthy control group and results were statistically significant (p 0.001 and p = 0.002). Again, leukocytes, cholesterol, LDL cholesterol, triglyceride levels were higher in died AKI patients (p = 0.016, p = 0.032, p = 0.03 and p = 0.026) Addition to these values in patients who died, Infection and comorbidity diseases were important factors. In infections found sepsis and pneumonia. HDL cholesterol levels did not differ between patients (p = 0.52). Conclusion: Inflammation, malnutrition, sepsis are highly prevalent diseases in AKI patients. Patients who died in AKI (% 4,94), CRP, PCT, SAA, albumin, and cholesterol levels were higher. Treatment and following these values were important.

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Inflammation , infection , malnutrition , acute kidney injury

Kocatepe Medical Journal

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Kocatepe Medical Journal