EVALUATION OF THE EFFECTS OF DEXMEDETOMIDINE INFUSION WITH OR WITHOUT PRELOADING THAT IS APPLIED BY THE AIM OF SEDATION ON SPINAL ANAESTHESIA ON HEMODINAMI AND SEDATION RETROSPECTIVELY

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OBJECTIVE: The aim of this study is to compare the effects of infusion of dexmedetomidine in spinal anaesthesia with or without preloading that is applied by the aim of sedation on regional anaesthesia on sedation and hemodinamia retrospectively. MATERIAL AND METHODS: The medical and anaesthesia records of total 60 patients were evaluated retrospectively that lower abdominal and extremity surgery was applied with spinal anaesthesia and that dexmedetomidine infusion was applied for the aim of sedation between November 2003 - January 2015. The patients were divided into two groups as dexmedetomidine infusion with preloading; Group A (n=40) and dexmedetomidine infusion without preloading; Group B (n=20).The hemodynamic values Heart Rate (HR), Mean Arterial Pressure (MAP) and Ramsey Sedation Score (RSS) were evaluated on examined cases. RESULTS: The HR was decreased statistically significantly in Group A from the 10^th minutes of the spinal anaesthesia to the 50^th minutes of operation; and decreased statistically significantly from 20^th minutes of the spinal anaesthesia to 50^th minutes of operation. MAP was decreased statistically significantly according to control values in all time intervals from 15^th minutes of spinal anaesthesia to 50^th minutes of operation in Group A and from 10^th minutes of spinalanaesthesia to 50^th minutes of operation in Group B.The RSS values were found statistically significantly different between two groups on 5^th, 25^th, and 30^th minutes. CONCLUSIONS: It is observed retrospectively that the proper sedation level can be reached without dexmedetomidine preloading on spinal anaesthesia applied cases by minimising hemodynamic instability.

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Spinal anaesthesia , Sedation , Dexmedeto , midine

Kocatepe Medical Journal

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Kocatepe Medical Journal