Title :
Compact label-free biosensor using VCSEL-based measurement system
Author :
Mateus, Carlos F R ; Huang, Michael C Y ; Li, Peter ; Cunningham, Brian T. ; Chang-Hasnain, Connie J.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Univ. of California, Berkeley, CA, USA
fDate :
7/1/2004 12:00:00 AM
Abstract :
We report an ultracompact label-free biosensor that uses a vertical-cavity surface-emitting laser (VCSEL)-based measurement system for the characterization of biomolecular interactions. It consists of a VCSEL, a plastic guided-mode resonant filter, and two p-i-n detectors. The system has demonstrated very high sensitivity to molecules on top of the sensor.
Keywords :
biomedical transducers; biosensors; laser applications in medicine; measurement by laser beam; molecular biophysics; optical sensors; optical waveguide filters; photodetectors; surface emitting lasers; VCSEL; biomolecular interactions; label-free biosensor; p-i-n detectors; resonant filter; vertical-cavity surface-emitting laser; Biosensors; Detectors; Filters; PIN photodiodes; Plastics; Resonance; Sensor phenomena and characterization; Sensor systems; Surface emitting lasers; Vertical cavity surface emitting lasers;
Journal_Title :
Photonics Technology Letters, IEEE
DOI :
10.1109/LPT.2004.828851
