• DocumentCode
    1023580
  • Title

    Ideal observers and optimal ROC hypersurfaces in N-class classification

  • Author

    Edwards, Darrin C. ; Metz, Charles E. ; Kupinski, Matthew A.

  • Author_Institution
    Dept. of Radiol., Univ. of Chicago, IL, USA
  • Volume
    23
  • Issue
    7
  • fYear
    2004
  • fDate
    7/1/2004 12:00:00 AM
  • Firstpage
    891
  • Lastpage
    895
  • Abstract
    The likelihood ratio, or ideal observer, decision rule is known to be optimal for two-class classification tasks in the sense that it maximizes expected utility (or, equivalently, minimizes the Bayes risk). Furthermore, using this decision rule yields a receiver operating characteristic (ROC) curve which is never above the ROC curve produced using any other decision rule, provided the observer\´s misclassification rate with respect to one of the two classes is chosen as the dependent variable for the curve (i.e., an "inversion" of the more common formulation in which the observer\´s true-positive fraction is plotted against its false-positive fraction). It is also known that for a decision task requiring classification of observations into N classes, optimal performance in the expected utility sense is obtained using a set of N-1 likelihood ratios as decision variables. In the N-class extension of ROC analysis, the ideal observer performance is describable in terms of an (N2-N-1)-parameter hypersurface in an (N2-N)-dimensional probability space. We show that the result for two classes holds in this case as well, namely that the ROC hypersurface obtained using the ideal observer decision rule is never above the ROC hypersurface obtained using any other decision rule (where in our formulation performance is given exclusively with respect to between-class error rates rather than within-class sensitivities).
  • Keywords
    medical image processing; sensitivity analysis; Bayes risk; N-class classification; decision rule; expected utility; false-positive fraction; ideal observers; optimal ROC hypersurfaces; receiver operating characteristic; true-positive fraction; Cancer; Error analysis; Optical receivers; Optical sensors; Performance analysis; Probability density function; Radiology; Sensitivity; Signal to noise ratio; Utility theory; Bayes Theorem; Data Interpretation, Statistical; Decision Theory; Humans; Likelihood Functions; Models, Statistical; Probability; ROC Curve;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/TMI.2004.828358
  • Filename
    1309712