DocumentCode :
1036855
Title :
Ultrasonically Actuated Silicon Microprobes for Cardiac Signal Recording
Author :
Xi Chen ; Lal, A. ; Riccio, M.L. ; Gilmour, R.F.
Author_Institution :
Sch. of Electr. & Comput. Eng., Cornell Univ., Ithaca, NY
Volume :
53
Issue :
8
fYear :
2006
Firstpage :
1665
Lastpage :
1671
Abstract :
In this paper, we report on ultrasonically actuated silicon thin microprobes that successfully penetrated canine cardiac tissue in vitro, and recorded the electrophysiological signals from multiple sites simultaneously within the heart wall. The penetration force-maximum force encountered by the probe during penetration-is found to reduce with increasing ultrasonic driving voltage, on both excised canine right ventricular muscle and chicken breast muscle. The rate of force decrease varies with tissue type and microprobe dimension. With ultrasonic actuation, the silicon microprobes are inserted into isolated perfused canine heart without breakage or significant buckling, under 10Vpp actuating voltage. Recordings were obtained from isolated perfused canine heart during pacing, following the induction of ventricular tachycardia, and during the transition from ventricular tachycardia to ventricular fibrillation. Local conduction velocity of 0.60plusmn0.03 m/s was observed from the multichannel recordings from the canine right ventricular wall under epicardial pacing. The application of the ultrasonic microprobes in cardiac electrophysiology study can provide information for reconstruction of electrical wave propagation within the heart, which is important to understanding the mechanisms of cardiac arrhythmias
Keywords :
bioelectric phenomena; biomedical equipment; biomedical ultrasonics; cardiology; medical control systems; microactuators; microelectrodes; muscle; Si; canine cardiac tissue; cardiac arrhythmias; cardiac electrophysiology; cardiac signal recording; chicken breast muscle; electrical wave propagation reconstruction; electrophysiological signals; epicardial pacing; excised canine right ventricular muscle; heart wall; isolated perfused canine heart; local conduction velocity; microprobe dimension; penetration force; tissue type; ultrasonic driving voltage; ultrasonically actuated silicon microprobes; ventricular tachycardia; Breast; Cardiac tissue; Electrophysiology; Fibrillation; Heart; In vitro; Muscles; Probes; Silicon; Voltage; Cardiac arrhythmia; penetration force; silicon microprobe; ultrasonic horn; Animals; Body Surface Potential Mapping; Dogs; Equipment Design; Equipment Failure Analysis; Heart Conduction System; Miniaturization; Silicon; Tachycardia, Ventricular; Transducers; Ultrasonography;
fLanguage :
English
Journal_Title :
Biomedical Engineering, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9294
Type :
jour
DOI :
10.1109/TBME.2006.877808
Filename :
1658161
Link To Document :
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