• DocumentCode
    1038608
  • Title

    Detection of Uterine MMG Contractions Using a Multiple Change Point Estimator and the K-Means Cluster Algorithm

  • Author

    La Rosa, Patricio S. ; Nehorai, Arye ; Eswaran, Hari ; Lowery, Curtis L. ; Preissl, Hubert

  • Author_Institution
    Washington Univ. in St. Louis, St. Louis
  • Volume
    55
  • Issue
    2
  • fYear
    2008
  • Firstpage
    453
  • Lastpage
    467
  • Abstract
    We propose a single channel two-stage time-segment discriminator of uterine magnetomyogram (MMG) contractions during pregnancy. We assume that the preprocessed signals are piecewise stationary having distribution in a common family with a fixed number of parameters. Therefore, at the first stage, we propose a model-based segmentation procedure, which detects multiple change-points in the parameters of a piecewise constant time-varying autoregressive model using a robust formulation of the Schwarz information criterion (SIC) and a binary search approach. In particular, we propose a test statistic that depends on the SIC, derive its asymptotic distribution, and obtain closed-form optimal detection thresholds in the sense of the Neyman-Pearson criterion; therefore, we control the probability of false alarm and maximize the probability of change-point detection in each stage of the binary search algorithm. We compute and evaluate the relative energy variation [root mean squares (RMS)] and the dominant frequency component [first order zero crossing (FOZC)] in discriminating between time segments with and without contractions. The former consistently detects a time segment with contractions. Thus, at the second stage, we apply a nonsupervised K-means cluster algorithm to classify the detected time segments using the RMS values. We apply our detection algorithm to real MMG records obtained from ten patients admitted to the hospital for contractions with gestational ages between 31 and 40 weeks. We evaluate the performance of our detection algorithm in computing the detection and false alarm rate, respectively, using as a reference the patients´ feedback. We also analyze the fusion of the decision signals from all the sensors as in the parallel distributed detection approach.
  • Keywords
    autoregressive processes; biological organs; biomagnetism; biomechanics; biomedical measurement; medical signal processing; muscle; obstetrics; pattern clustering; probability; sensor fusion; Neyman-Pearson criterion; RMS; Schwarz information criterion; asymptotic distribution; binary search method; dominant frequency component; false alarm rate; first-order zero crossing; gestational ages; magnetomyogram; model-based segmentation procedure; multiple change point estimator; nonsupervised K-means cluster algorithm; parallel distributed detection; piecewise constant time-varying autoregressive model; piecewise stationary; probability; relative energy variation; root mean squares; sensor signal fusion; signal preprocessing; single channel two-stage time-segment discriminator; time 31 week to 40 week; uterine MMG contraction detection; Change detection algorithms; Clustering algorithms; Detection algorithms; Pregnancy; Probability; Robustness; Silicon carbide; Statistical analysis; Statistical distributions; Testing; Autoregressive process; changepoint detection; magnetomyogram (MMG); uterine contraction; Action Potentials; Algorithms; Artificial Intelligence; Cluster Analysis; Diagnosis, Computer-Assisted; Electromyography; Female; Humans; Magnetics; Muscle Contraction; Pattern Recognition, Automated; Pregnancy; Uterine Contraction;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2007.912663
  • Filename
    4432743